Cyclosporine-induced Erythromelalgia

Treatment of primary erythromelalgia with cyclosporine.

A 28-year-old woman presented with severe, persistent burning pain in the legs and feet, with marked erythema, swelling, and warmth (Fig. 1, left-hand panels). The erythema had begun at the age off our years, with no associated disorder. After adolescence, the symptoms became continuous, with erythema that extended to the thighs and the development of live do-like lesions. Burning pain during t...

Erythromelalgia.

No treatment is consistently effective in the management of patients with erythromelalgia. There is a dearth of adequate studies examining the response of erythromelalgia to therapy. Most recommendations are suggested based on case reports, small case series, and anecdotal reports. The management of erythromelalgia is difficult and frequently involves a multidisciplinary approach. An approach t...

Erythromelalgia induced by nicardipine (inverse Raynaud's phenomenon?).

Cyclosporine-A Induced Gingival Overgrowth

Background. The link between the gingival overgrowth and cyclosporine pharmacokinetical variables, especially cyclosporine doses which appear to act as stimulator of the gingival proliferative changes, presents a field of interest of large number of researches. The existence of undefined association and/or interaction between the cyclosporine and periodontal variables, could be responsible for ...

Cyclosporine-induced infantile nodulocystic acne.

BACKGROUND In adult organ transplant recipients, nodulocystic acne induced by the use of cyclosporine can be treated successfully with isotretinoin. Cyclosporine's acnegenic effects in children and the pediatric response to treatment are less clear. OBSERVATIONS A 9-month-old boy presented with cysts and nodules on his face after he began cyclosporine therapy after a heart transplantation. We...